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GABAA PAMs improve the impact of GABA by making the channel open more continuously or for longer periods. Taking it in a approach apart from prescribed (reminiscent of crushing and snorting it). Taking more Xanax or taking it for longer intervals than supposed. Abusing benzodiazepines like Xanax may also simply result in overdose, especially if massive amounts are taken with other depressants like alcohol. If you happen to suspect someone is experiencing a benzodiazepine overdose, or any other substance overdose, name 911 instantly. Somebody with an anxiety disorder can change into out of the blue overwhelmed with emotions of nausea, panic, and fear, experiencing heart palpitations and hyperventilation. Do you wish to be shut sufficient to go to, or does the particular person have to get away from individuals and locations that encourage Xanax use? 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